DPCstruct | MC14875

Metacluster Properties and Pfam Annotations

Number of structural domains46
Mean domain length (aa)123 ± 18 aa
Standard deviation of domain lengths18.46
Length coefficient of variation0.15
Mean AlphaFold2 pLDDT confidence score81.85
Mean fraction of residues predicted as intrinsically disordered0.19
Mean length-normalized TM-Score0.54
Mean intra-cluster local Distance Difference Test score0.61
Mean intra-cluster sequence similarity (%)18.07
Pfam Score57.14
Assigned Pfam label(s) PF05772- PF07105

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2X2BH87 2-88 FHALCGDVSKQMTLNNEPLKLWQWKNVFVSGHWMVTTGAKESPLIRGIEGELLNIRESTSQMGKKRMSSLIEYSTAWAVQSGVKLRT
A0A2D7VZJ8 8-120 TSFDFKAKAIDAIRTASEGQVVTIQPRNRTTEQNSLYWALLQNLSEQYVNEDNRTFSADTWHEYFKQQYLPKDYVELPDGNVKEKER…
A0A1B9N5R5 1-149 None
A0A4Z0DJP1 84-221 None
A0A3D4XPW5 1-131 None
A0A7T2GKJ0 17-140 None
A0A316RAY2 4-118 None
A0A2V3Q3F9 1-103 None
A0A2G2PJ97 12-162 None
A0A0J6SGC8 2-123 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.