DPCstruct | MC14806

Metacluster Properties and Pfam Annotations

Number of structural domains12
Mean domain length (aa)117 ± 7 aa
Standard deviation of domain lengths6.74
Length coefficient of variation0.06
Mean AlphaFold2 pLDDT confidence score89.09
Mean fraction of residues predicted as intrinsically disordered0.37
Mean length-normalized TM-Score0.79
Mean intra-cluster local Distance Difference Test score0.79
Mean intra-cluster sequence similarity (%)31.89
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A401SWT2 101-223 FLVVPLAYSGKQPFRKGQDQWLHAGPPNNEYMDQNFQHLNGILNLPSSDVAIKEAFHNSQLVGRPLELWIYESVGKFWSATNTCTVE…
A0A4Y2ISU9 699-813 YNGHEVSSEQVKFLHNGPGQPYVDHDFSNVEALLGYANKSVQARQALSNSRRYGKDLKEWTDTLVSSFWSVQDTCFVNQPLHPSGGA…
A0A1S3QSL7 286-399 None
A0A3Q0JG78 3-115 None
A0A443S9P9 144-245 None
A0A6A4WL99 473-593 None
A0A0A9WGN7 366-479 None
G3HBF2 64-191 None
A0A4Z2F479 166-281 None
S4PXP3 98-222 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.