DPCstruct | MC14749

Metacluster Properties and Pfam Annotations

Number of structural domains60
Mean domain length (aa)227 ± 55 aa
Standard deviation of domain lengths55.08
Length coefficient of variation0.24
Mean AlphaFold2 pLDDT confidence score74.12
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.60
Mean intra-cluster local Distance Difference Test score0.59
Mean intra-cluster sequence similarity (%)21.42
Pfam Score100.00
Assigned Pfam label(s) CL0186

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
Q504E3 37-239 PESLLFVSTLDGNLHAVSKISGTIKWTLKEDPVLQVPTHVSEPAFLPDPNDGSLYSLGGKNNEGLTKLPFTIPELVQASPCRSSDGI…
A0A183JFG2 42-280 KIPNDSYILVHTLGGEILCVHRRSGHVKWKFDSGMLFLNYLHSVVLASALSASYDNGPLLVVDPISGSLYEYASSVSEFLFQLLDHS…
A0A0H2S1Y3 2-385 None
A0A267FYU7 286-598 None
A0A022RXM0 13-159 None
A0A7S3UGJ2 66-333 None
A0A5J4WXM0 10-229 None
H9JGH9 2-218 None
A0A7R8ZAU1 44-225 None
A0A6J8AXM2 176-380 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.