DPCstruct | MC14691

Metacluster Properties and Pfam Annotations

Number of structural domains914
Mean domain length (aa)217 ± 41 aa
Standard deviation of domain lengths41.34
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score86.32
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.48
Mean intra-cluster local Distance Difference Test score0.44
Mean intra-cluster sequence similarity (%)14.86
Pfam Score70.51
Assigned Pfam label(s) CL0023- CL0748- PF13154- PF19898- CL0413

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A250DKS7 1-431 None
A0A1Q2R9M8 10-301 None
A0A7S2HN69 7-179 None
A0A2L2NZH9 194-539 None
A0A2L2P0P0 595-800 None
A0A1Z4QLR4 20-249 None
A0A817A942 75-301 None
A0A2K8SI55 11-321 None
A0A2V8URX9 186-438 None
B1Y3C6 122-316 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.