DPCstruct | MC14691

Metacluster Properties and Pfam Annotations

Number of structural domains914
Mean domain length (aa)217 ± 41 aa
Standard deviation of domain lengths41.34
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score86.32
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.48
Mean intra-cluster local Distance Difference Test score0.44
Mean intra-cluster sequence similarity (%)14.86
Pfam Score70.51
Assigned Pfam label(s) CL0023- CL0748- PF13154- PF19898- CL0413

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6D0M065 1-140 RERVMFPIRDKRGRVIGFGGRVLGDALPKYLNSPETDIFHKGRQLYGLYEAQQDNAEPPRLLVVEGYMDVVALAQYDINYAVASLGT…
A0A072URK0 44-251 EESLGLEPLGPKLVAYFKERLISEKTLSRNSVRQLSDEKNVIAFTYKQNGLIVGCKYRTMEKRFWQGKVIDKVLYGLDDISHATEII…
A0A6M0F197 55-258 None
A0A2T2W1C7 62-314 None
A0A416PFK1 113-368 None
A0A357NJC3 11-201 None
A0A837Q6Y5 63-342 None
A0A139PJD1 8-365 None
A0A6J0PLF9 40-255 None
A0A0D0RBM4 88-324 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.