DPCstruct | MC14688

Metacluster Properties and Pfam Annotations

Number of structural domains10
Mean domain length (aa)233 ± 18 aa
Standard deviation of domain lengths17.52
Length coefficient of variation0.08
Mean AlphaFold2 pLDDT confidence score88.79
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.93
Mean intra-cluster local Distance Difference Test score0.89
Mean intra-cluster sequence similarity (%)53.68
Pfam Score100.00
Assigned Pfam label(s) CL0044

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A257AX73 117-335 MARDEGRHSGFIRLAMRDINADLDLQLLQGEKEFVSMHPKIILYTTYLSEVIGYFRYINIYSHLQAHPEHRYHPIFKYFGGWCQDEL…
A0A2Z6D1T7 1-233 MARDEARHAGFLNKAMGDFKLSLDLATVTKTRTYTFFPIEWVLYTVYLSEKIGYWRYIIIYRHLEQHPEHQFYPIFRYFESWCQDEN…
A0A453ERJ6 13-236 None
A0A7J7Q8W8 154-403 None
B9EV82 159-408 None
A0A6V7PRL6 158-352 None
A0A2P6VQN2 156-408 None
A0A087SQT0 440-687 None
A0A699YKP6 105-325 None
A0A258X664 49-282 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.