DPCstruct | MC14603

Metacluster Properties and Pfam Annotations

Number of structural domains38
Mean domain length (aa)139 ± 23 aa
Standard deviation of domain lengths23.28
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score87.99
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.63
Mean intra-cluster local Distance Difference Test score0.62
Mean intra-cluster sequence similarity (%)22.89
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A3G8MCL5 1-85 MCSKLLGDTYYAALEQQRSDGAREVFALVCLTYYNPRDPEGFIFGYKDMTEAMGPCASDCPEDILDLLTPTDRPYAIAWRARCRE
A0A2T4MWN1 1-146 MGWTFINKPDNIKQFFTEMFEDDGDKIKYKVLDAKIVSLRTLYMAIEKTYPESKDRDVFGLVVLLDMTSARKEYHNFGYKIIDENAC…
A0A7W5X5I3 1-157 None
A0A8A9F4X6 1-127 None
A0A7W7EAE1 1-164 None
B6WRT4 1-116 None
A0A509J6Z7 19-155 None
A0A246BX54 4-149 None
A0A2W4YER3 1-134 None
A0A7T8M662 1-133 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.