DPCstruct | MC146

Metacluster Properties and Pfam Annotations

Number of structural domains102
Mean domain length (aa)124 ± 27 aa
Standard deviation of domain lengths27.10
Length coefficient of variation0.22
Mean AlphaFold2 pLDDT confidence score84.04
Mean fraction of residues predicted as intrinsically disordered0.30
Mean length-normalized TM-Score0.71
Mean intra-cluster local Distance Difference Test score0.69
Mean intra-cluster sequence similarity (%)24.68
Pfam Score88.76
Assigned Pfam label(s) CL0758- PF04874- CL0015- PF01778

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A9U7H9 4-106 VSDDLIWLLVKNSNRFLVKRNGNNNNSVTFSSEPNNLYNLNTFKYSGLANKKSVAIAPAEGLSVVLTTTKTKKRNQPAKLRHNSLLK…
A0A6P9FKL5 2-72 SAHLRWMVVRNCSSFPIKRNKQTYSTEPNNLKARNSFRYNGLIHRKTVGVEPAADGKGVVVVMKRRSGQRK
A0A6V7WWR2 95-245 None
A0A212C6A1 2-99 None
A0A452T226 2-88 None
J5TMW7 99-213 None
A0A6D2I5Y7 3-98 None
A0A7S1Y0J8 46-186 None
R9P3R1 100-227 None
A0A7S3JMK9 9-145 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.