DPCstruct | MC14599

Metacluster Properties and Pfam Annotations

Number of structural domains12
Mean domain length (aa)86 ± 8 aa
Standard deviation of domain lengths8.49
Length coefficient of variation0.10
Mean AlphaFold2 pLDDT confidence score76.47
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.74
Mean intra-cluster local Distance Difference Test score0.80
Mean intra-cluster sequence similarity (%)53.94
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6S7LX18 1-93 MDLIESIHDIPVQNPSVEDFSASDLNWIKFGTPEHHDDVALIPYARAEEFIIGECSNVECPTRFHIERGRKRSLGSLMEFKSDEYLE…
A0A067D2C6 1-90 MDIVESLFDIQVQDPPEEDFSSIDLTWTKFGTAEHHDEVALIPYARVDSFIIGECSNVECPTRFHIERGRKRSRGSLKEYKDDEYLE…
A0A1S3Y6X4 7-98 None
A0A830CF18 26-91 None
A0A565BRS8 7-81 None
A0A445BZB9 186-275 None
A0A5A7T5N1 7-87 None
A0A6A2X7D4 45-135 None
A0A540LCU7 154-252 None
A0A660KX92 167-251 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.