DPCstruct | MC14560

Metacluster Properties and Pfam Annotations

Number of structural domains94
Mean domain length (aa)241 ± 52 aa
Standard deviation of domain lengths52.07
Length coefficient of variation0.22
Mean AlphaFold2 pLDDT confidence score81.01
Mean fraction of residues predicted as intrinsically disordered0.18
Mean length-normalized TM-Score0.63
Mean intra-cluster local Distance Difference Test score0.63
Mean intra-cluster sequence similarity (%)24.74
Pfam Score79.86
Assigned Pfam label(s) CL0023- CL0220- PF08393- PF17852- CL0671

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A3S5A5C9 1-126 MITEEHLRSLMFGDYMDPDAFAEDRRYEEVKDINRLYPIAEHYLNDFNSSNKNKMNLVIFRYVLEHLSRISRILRSPGGNALLVGVG…
A0A060YGI1 463-710 LFTPCVLTQWVLSLLRYDLSAGNCNITDSVLEVVAYEAKRLFRDRLVSSKDIHSFDNILSSVIRGDWGSDALDNMTDGFYVTWGASE…
A0A812LF56 585-891 None
A0A0N4VVJ1 25-264 None
A0A7J6UIT8 218-482 None
A0A813PS57 23-267 None
A0A5J4V7Y4 143-389 None
T1GEP1 8-169 None
E7FFM4 824-1103 None
A0A821HPW7 10-214 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.