DPCstruct | MC14529

Metacluster Properties and Pfam Annotations

Number of structural domains1294
Mean domain length (aa)153 ± 25 aa
Standard deviation of domain lengths25.00
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score80.27
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.58
Mean intra-cluster local Distance Difference Test score0.52
Mean intra-cluster sequence similarity (%)16.79
Pfam Score94.76
Assigned Pfam label(s) CL0023- CL0481- CL0126- CL0109- CL0324

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7G8VKJ1 10-166 TPAPESGFASGTRIHTKQGLQPIEDIRAGDWVLTHAEQRPPPPRRRHHGEYQYRRVTLMTSVEVQSMVRVTLQNFADGIKDTLLVAP…
D0W6I4 2-122 VKTADGYKAIAHIQTGEYVFAKDETSGKTGYKPVTARYGNPYRETVYIEVSDGIGNSQTLISNRIHPFYSDGKWIKAEDLKAGIRLL…
A0A2N0PTT4 255-421 None
A0A2D7YW40 581-762 None
A0A7K0BRU8 231-381 None
A0A1P8WKC0 95-265 None
A0A1M3Q885 354-507 None
A0A1M3Q1A5 13-177 None
B8IH48 524-656 None
A0A1N7DGY0 32-180 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.