DPCstruct | MC14486

Metacluster Properties and Pfam Annotations

Number of structural domains54
Mean domain length (aa)180 ± 32 aa
Standard deviation of domain lengths32.47
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score84.82
Mean fraction of residues predicted as intrinsically disordered0.29
Mean length-normalized TM-Score0.61
Mean intra-cluster local Distance Difference Test score0.53
Mean intra-cluster sequence similarity (%)18.88
Pfam Score88.89
Assigned Pfam label(s) PF04213- PF07589

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1Q3T2N1 2-120 TALRWGIKKSLHEYVRSAEGSIEVADGARLDGDEVIFPADDGVEGAFTGSVRFLAHGGMMDWRLAAPHLEDGGSIVTIGGRRGARVQ…
A0A169S6H3 36-219 AAVATTDDVAVVTAENSLDWGFKASWRNYVTGPWTAGTVDATEGATVNEDGTYNFTLGSGSTYDADSEQGQLNYEGTVRFASALHGF…
A0A5C8I9U9 145-341 None
A9WRJ6 755-926 None
A0A1M7P917 10-160 None
A0A1Q8JN04 95-297 None
A0A7X6CMJ5 195-357 None
A0A3E0D0K2 12-134 None
A0A1R4FE36 2-177 None
A0A2S9A6I4 18-215 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.