DPCstruct | MC14477

Metacluster Properties and Pfam Annotations

Number of structural domains80
Mean domain length (aa)164 ± 31 aa
Standard deviation of domain lengths30.61
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score78.91
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.52
Mean intra-cluster local Distance Difference Test score0.65
Mean intra-cluster sequence similarity (%)27.07
Pfam Score98.21
Assigned Pfam label(s) PF04434- PF02617- PF02207

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A0C2NKK1 4-186 ISGRMNTIIIKGLLVSSNDTGTHVREIFTIDRLESLVGVALEEYIFEEVGPDIQKWFFSEHCNLGMCTNVISAGDAIYSCLECQQHD…
A0A444TZ31 15-145 AAHLKADLNRTDNSSGVHQLQELLDSVLNPERPAGDTEALEWCKCLLAGGEEFEEFCKTVRSYDNATLCGLVWTANFVAYRCRTCGI…
A0A182J7J5 13-138 None
B4H3V1 154-326 None
A0A2H2IT18 50-243 None
A0A7R9B0N1 5-131 None
A0A6J3C282 33-250 None
A0A4C1U753 10-111 None
A0A813US08 64-245 None
A0A2W1BT50 18-176 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.