DPCstruct | MC14455

Metacluster Properties and Pfam Annotations

Number of structural domains13
Mean domain length (aa)140 ± 24 aa
Standard deviation of domain lengths23.87
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score88.18
Mean fraction of residues predicted as intrinsically disordered0.17
Mean length-normalized TM-Score0.74
Mean intra-cluster local Distance Difference Test score0.66
Mean intra-cluster sequence similarity (%)24.08
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2E1UWD6 31-164 PGARSLINTGKATLRPKYGIMNLFGYDPKYKETLPYYDRFPLIFPLEPARGGFRGLNFHYLQPGARVAFLRQLAEYASDSNFDKKTR…
A0A381UU62 7-129 MKGSNLVQKRRMTKARLTLFSYKAKHEKTLPYYDRFPLSMIIGKDVDGFIGLNFHYLPYQYRARLLDAVAFGNVINWNTLKRNKVTR…
A0A2E9PUQ4 34-148 None
A0A496ZME6 22-220 None
A0A661HJZ2 106-254 None
A0A350PJ04 65-203 None
A0A7Z9QIA7 87-256 None
A0A2D8EN02 37-182 None
A0A382JZW0 1-135 None
A0A354GH62 4-113 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.