DPCstruct | MC14446

Metacluster Properties and Pfam Annotations

Number of structural domains824
Mean domain length (aa)146 ± 33 aa
Standard deviation of domain lengths32.70
Length coefficient of variation0.22
Mean AlphaFold2 pLDDT confidence score76.72
Mean fraction of residues predicted as intrinsically disordered0.37
Mean length-normalized TM-Score0.55
Mean intra-cluster local Distance Difference Test score0.69
Mean intra-cluster sequence similarity (%)26.06
Pfam Score99.45
Assigned Pfam label(s) CL0277- CL0108- CL0123- PF09316- CL0073

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2I1H6N8 696-830 None
A0A2N0S7M8 164-311 None
A0A6A6LR48 353-572 None
A0A6A6LV74 1-114 None
A0A6A6LYE2 1-86 None
D2VWA0 1-222 None
U9U8G5 153-299 None
A0A6J2Y419 284-436 None
A2DPC5 4-163 None
A0A0E0A7U7 334-469 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.