DPCstruct | MC14446

Metacluster Properties and Pfam Annotations

Number of structural domains824
Mean domain length (aa)146 ± 33 aa
Standard deviation of domain lengths32.70
Length coefficient of variation0.22
Mean AlphaFold2 pLDDT confidence score76.72
Mean fraction of residues predicted as intrinsically disordered0.37
Mean length-normalized TM-Score0.55
Mean intra-cluster local Distance Difference Test score0.69
Mean intra-cluster sequence similarity (%)26.06
Pfam Score99.45
Assigned Pfam label(s) CL0277- CL0108- CL0123- PF09316- CL0073

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A5P1F0J7 39-154 None
A0A0V0QIU2 131-287 None
A0A7S0J727 73-236 None
A0A0V0R1R4 915-1053 None
A0A199VZS5 1-78 None
H3BE80 215-347 None
A0A819PDE0 757-888 None
A0A1E5RSZ7 21-150 None
A0A1L9TXI5 402-547 None
A0A6G1EEG3 122-251 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.