DPCstruct | MC14446

Metacluster Properties and Pfam Annotations

Number of structural domains824
Mean domain length (aa)146 ± 33 aa
Standard deviation of domain lengths32.70
Length coefficient of variation0.22
Mean AlphaFold2 pLDDT confidence score76.72
Mean fraction of residues predicted as intrinsically disordered0.37
Mean length-normalized TM-Score0.55
Mean intra-cluster local Distance Difference Test score0.69
Mean intra-cluster sequence similarity (%)26.06
Pfam Score99.45
Assigned Pfam label(s) CL0277- CL0108- CL0123- PF09316- CL0073

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7N0UE29 5-81 LRRGPWTDEEDRILSSYIAKHGEGRWNSLARCAGLNRTGKSCRLRWLNYLRPDVRRGNISLEEQLLILELHSRWGNR
A0A2I7ZAS7 7-162 CYKQKLRKGLWSPEEDDKLLRHITQYGHGCWSSVPKLAGLAETASLSVQTARGLQRCGKSCRLRWINYLRPDLKRGAFSQEEENLII…
A0A5K4FF61 30-217 None
A0A0A0LUR0 20-98 None
A0A1V9YTT0 15-220 None
A0A1U7Y6T4 1-178 None
A0A5N6PD63 9-123 None
A0A5N6PUH4 5-110 None
A0A5B6VVC4 4-127 None
A9TCW1 2-103 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.