DPCstruct | MC14436

Metacluster Properties and Pfam Annotations

Number of structural domains71
Mean domain length (aa)89 ± 17 aa
Standard deviation of domain lengths17.46
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score81.37
Mean fraction of residues predicted as intrinsically disordered0.32
Mean length-normalized TM-Score0.69
Mean intra-cluster local Distance Difference Test score0.72
Mean intra-cluster sequence similarity (%)36.01
Pfam Score98.78
Assigned Pfam label(s) CL0317- CL0511

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6A4W1Q1 130-184 RPRGEGMTPYQGKKRCFGEYKCSKCKRKWMSGNSWANMAQMCKKCRLFVYPHKQV
A0A6J1NAG0 9-94 EAKEGEGLTPYQGKRRSFGEFKCPQCQRRWMSANSWANSGQDCSKCKINVYPHRQMRLDNPGGLDKSDPTKRHPRELCQRCREIGD
K7F236 89-182 None
A0A6S7GWR7 579-662 None
A0A6S7G597 970-1055 None
A0A7M5V1D2 11-100 None
A0A7R9KQE8 365-465 None
A0A182FU96 326-418 None
H3BGB9 24-106 None
A0A812QIS0 272-345 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.