DPCstruct | MC14425

Metacluster Properties and Pfam Annotations

Number of structural domains48
Mean domain length (aa)146 ± 16 aa
Standard deviation of domain lengths16.27
Length coefficient of variation0.11
Mean AlphaFold2 pLDDT confidence score83.68
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.75
Mean intra-cluster local Distance Difference Test score0.69
Mean intra-cluster sequence similarity (%)26.12
Pfam Score100.00
Assigned Pfam label(s) PF14108

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A0M0KAR5 8-153 IDTCVSIDTFAPQFLWLLIVAAPRSTLTRSVMGSIGPILALSLVHLAVVITAASAPGGTEPIAIFADVFDPAKNQLEGMERLFAVRD…
A0A7R8AZD6 3-141 PFELSNVVVLPFWALMILAPLWSVTRRLIGSPWIVAPPALIYLATLVPVASIVLPAVVNPVPAEIAALLGTPTGTALAWAHFVAFDL…
A0A803LAW1 44-189 None
A0A7S3V3A9 13-157 None
A0A3L7YS58 7-137 None
C1EE22 65-251 None
A0A354VZQ8 28-169 None
A0A2S0UKL2 9-107 None
A0A0G4H0Z3 69-226 None
A0A2E5RW95 59-218 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.