DPCstruct | MC14396

Metacluster Properties and Pfam Annotations

Number of structural domains24
Mean domain length (aa)99 ± 12 aa
Standard deviation of domain lengths11.70
Length coefficient of variation0.12
Mean AlphaFold2 pLDDT confidence score86.30
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.90
Mean intra-cluster local Distance Difference Test score0.91
Mean intra-cluster sequence similarity (%)53.91
Pfam Score86.67
Assigned Pfam label(s) CL0023- PF16897- CL0072

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A016WPE5 220-314 FREDATVDEFIDVIQGNRVYVPCIYVYNKIDQISIEEVDRLARIPHHVVISCEMNLNMDYLLEKIWEYLALVRVYTKKPGNAPDLGP…
A0A1I8C746 139-252 LDEDLVKQILGEYRIHNADITLKYDASVDDLIDVIEGNRVYIPCIYVLNKIDQITITELDVIRKVKHCCPISAQEKWNFDELLAMIW…
A0A2Z7DAG6 570-663 None
A0A3S3Q635 206-299 None
A0A0D2XE44 118-195 None
A0A0D7A5T6 162-252 None
A0A5D6XKX2 222-314 None
A0A6P5GHT3 210-312 None
A0A2P6NHR1 231-330 None
M5ECR4 221-320 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.