DPCstruct | MC14355

Metacluster Properties and Pfam Annotations

Number of structural domains319
Mean domain length (aa)170 ± 35 aa
Standard deviation of domain lengths35.47
Length coefficient of variation0.21
Mean AlphaFold2 pLDDT confidence score83.34
Mean fraction of residues predicted as intrinsically disordered0.48
Mean length-normalized TM-Score0.42
Mean intra-cluster local Distance Difference Test score0.66
Mean intra-cluster sequence similarity (%)20.76
Pfam Score98.79
Assigned Pfam label(s) PF03793- CL0159- CL0202

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2W4MT98 4-141 GPRTVTVPDVRRLTRAEAENQLLQLGLRVGAVTEVFAQDVDAGRVAEQSPPPGTQVQEGSVVDLKISRGTRRVPNLVGRTLAEAPAQ…
A0A7J9WC22 102-265 VADRSYLKGTQPTEVCREPTGPPTQDVPSVVGLPLHAASRLLEDAGLRVRRRAAVSATLPPGYVIRQDPDAGRAQRLRGGYRVTIWV…
A0A1V8QFI3 144-384 None
A0A2N5YPZ1 6-126 None
A0A7J9TVW9 53-212 None
A0A6G2HDI9 97-245 None
A0A350MV85 13-197 None
A0A7W0P420 90-241 None
A0A556MNJ3 148-302 None
A0A0X3QJJ6 563-743 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.