DPCstruct | MC14354

Metacluster Properties and Pfam Annotations

Number of structural domains72
Mean domain length (aa)233 ± 64 aa
Standard deviation of domain lengths64.10
Length coefficient of variation0.27
Mean AlphaFold2 pLDDT confidence score89.95
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.60
Mean intra-cluster local Distance Difference Test score0.54
Mean intra-cluster sequence similarity (%)15.40
Pfam Score50.83
Assigned Pfam label(s) PF19290- PF19289- PF01523- CL0334

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7J9W8U3 110-317 VLAAALSAGAEFAEVYAEQRRSRTVRLDDRRIESLTSGRDRGAGIRVQRGAQTAYAYTNVLSRHALLDAARVAAAGVQGSSETSVAD…
A0A3R6AYM2 3-210 EKILQAIRQFQIETYLVTEKTVEGAELYFIKKELDMRRMKQDAVSAVTIYRDFETDGKKMRGSANINIFPEMTQEEVDEAVKGAYYA…
M6YAD6 426-675 None
A0A7C7VGQ2 79-410 None
A0A5C6TZX4 6-255 None
A0A430EF27 13-204 None
A0A7E4SGM3 789-1052 None
A0A6J4HAS7 6-174 None
A0A2V9GGL0 44-303 None
T2RF53 6-195 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.