DPCstruct | MC14331

Metacluster Properties and Pfam Annotations

Number of structural domains248
Mean domain length (aa)140 ± 29 aa
Standard deviation of domain lengths29.06
Length coefficient of variation0.21
Mean AlphaFold2 pLDDT confidence score90.43
Mean fraction of residues predicted as intrinsically disordered0.32
Mean length-normalized TM-Score0.68
Mean intra-cluster local Distance Difference Test score0.67
Mean intra-cluster sequence similarity (%)21.30
Pfam Score55.56
Assigned Pfam label(s) PF07553- PF02631

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2A9ERZ4 189-283 GTVAQQNAKRSAEDYLAFTAFSRSGLIGQLEFEGFSTEDATWGVDHLTVDWNEQAAKSAAQYLDFTSFSRSGLIEQLIFEGFTPEQA…
A0A7X9C1K5 194-332 SREQKNALQKAKDYLNYSSFSKVGLYDQLIYEQFPNDAVQFAIDHIEVDWHDQAFQKGNDYLEYSAFSYQGLYDQLAYEGFENNEIQ…
A0A1Y6ENT1 2-142 None
H1LGR0 5-157 None
A0A1T4LWC2 44-196 None
A0A323VC90 3-79 None
A0A1R4G3S6 2-151 None
A0A4V2MM57 10-193 None
A0A150NRA5 40-147 None
A0A5N9BT66 28-195 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.