DPCstruct | MC14305

Metacluster Properties and Pfam Annotations

Number of structural domains15
Mean domain length (aa)87 ± 8 aa
Standard deviation of domain lengths7.63
Length coefficient of variation0.09
Mean AlphaFold2 pLDDT confidence score70.58
Mean fraction of residues predicted as intrinsically disordered0.33
Mean length-normalized TM-Score0.69
Mean intra-cluster local Distance Difference Test score0.80
Mean intra-cluster sequence similarity (%)45.99
Pfam Score100.00
Assigned Pfam label(s) CL0072

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A445EB34 21-98 VEITLFPNDPLRLKDVFERLTSLRGSGIPLQYSWSCKRNYKSGYVWCDLALNDIIHPAEGAKYILKGSELVQASSGYS
A0A446SCS8 3-96 LAQHPHQPLRLKDVMDKLTLLRGKGMPALFSWSCKRNYKNGYVWNDLSESDVIYPSDGVEYVLKGSEIFPGCSSGNHHANPSPSLTC…
A0A2K1IYX3 56-150 None
A0A453RSD0 20-107 None
A0A438G1J9 160-257 None
A0A0A9CW32 3-76 None
A0A540M8S5 23-107 None
A0A835IX79 6-91 None
A0A453FNZ7 1-83 None
N1R1D2 5-92 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.