DPCstruct | MC143

Metacluster Properties and Pfam Annotations

Number of structural domains23
Mean domain length (aa)78 ± 4 aa
Standard deviation of domain lengths3.87
Length coefficient of variation0.05
Mean AlphaFold2 pLDDT confidence score80.98
Mean fraction of residues predicted as intrinsically disordered0.27
Mean length-normalized TM-Score0.80
Mean intra-cluster local Distance Difference Test score0.88
Mean intra-cluster sequence similarity (%)41.89
Pfam Score100.00
Assigned Pfam label(s) PF04380

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1F8VE87 1-79 MIDPKSMNDIVQRLVDALPKGLTNLPKDLEQNFRSVLHSAFNKMDLVTREEFDAQTKVLHRTREKLEQLEKKIQHMEHR
A0A5C2HH62 2-76 EQRVEALTSQLLKLLPADVALLKRDLKQQIEGVLQQAFIEMELVTREEFEIQQKVLARSRQKLEQLERRLAELEQ
A0A2N1YN99 1-79 None
A0A8A6AXN5 1-80 None
A0A661FX83 27-110 None
A0A1G0IB05 1-83 None
K2BA36 26-106 None
A0A3D4UAT6 4-80 None
A0A1I6HLD0 1-77 None
A0A523M9V4 2-83 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.