DPCstruct | MC14295

Metacluster Properties and Pfam Annotations

Number of structural domains1332
Mean domain length (aa)215 ± 47 aa
Standard deviation of domain lengths46.78
Length coefficient of variation0.22
Mean AlphaFold2 pLDDT confidence score86.80
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.42
Mean intra-cluster local Distance Difference Test score0.42
Mean intra-cluster sequence similarity (%)14.22
Pfam Score85.21
Assigned Pfam label(s) PF01775- PF10288- CL0113- CL0020- CL0015

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7X8VJ40 99-263 None
A0A4R1GHV1 3-219 None
A0A812P2J6 535-720 None
A0A813A846 331-539 None
A0A1C3KZX3 305-477 None
M5E736 692-1038 None
A0A2I2YYS5 3-179 None
A0A6M1QAL9 7-212 None
U1HSA2 363-530 None
A0A838VB54 2-192 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.