DPCstruct | MC14295

Metacluster Properties and Pfam Annotations

Number of structural domains1332
Mean domain length (aa)215 ± 47 aa
Standard deviation of domain lengths46.78
Length coefficient of variation0.22
Mean AlphaFold2 pLDDT confidence score86.80
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.42
Mean intra-cluster local Distance Difference Test score0.42
Mean intra-cluster sequence similarity (%)14.22
Pfam Score85.21
Assigned Pfam label(s) PF01775- PF10288- CL0113- CL0020- CL0015

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7Y2FTI0 25-246 FKKMRKRLVRQVRQAIDDFSMLAGMDKRRWLVGLSGGKDSYGLLAILLDLQWRGLLPVELIACNLDQGQPNFPKHVLPEFLTRHGIA…
A0A2T1KDB9 135-367 EFVGTLQSELEGYIEGSSTVGILLSGGMDSRVVAGVLRKVQEQNPGGFDVVALTWGAAGSRDVVYAERIAHQFGWALEHFPISVETL…
A0A1A9X6P1 3-194 None
A0A259MIH9 190-415 None
A0A0F9NWI8 2-190 None
A0A4Z0Z7D6 39-247 None
A0A4Z0YNT3 25-267 None
A0A7X9PYX3 2-195 None
A0A496T4Q2 34-193 None
A0A1I5YH54 31-176 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.