DPCstruct | MC14250

Metacluster Properties and Pfam Annotations

Number of structural domains13
Mean domain length (aa)128 ± 16 aa
Standard deviation of domain lengths15.98
Length coefficient of variation0.12
Mean AlphaFold2 pLDDT confidence score72.32
Mean fraction of residues predicted as intrinsically disordered0.36
Mean length-normalized TM-Score0.42
Mean intra-cluster local Distance Difference Test score0.79
Mean intra-cluster sequence similarity (%)38.59
Pfam Score100.00
Assigned Pfam label(s) CL0214

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A453T758 2-129 LQLIFPGADPQLLRGYFEASGNVLDAAIRGFKDYLASGSALTNADAASSGVASDVLEMNARTNSIDWAELIVREMSAASDLIDAKSR…
A0A287E7N4 25-128 QLLRGYLEASGNVLDAAIRSFRGYLASDSATTNAGTSSSGVASDVPEMNAPTNSTEWAELIVKEILSASDMIDARDRSFRILEMFDK…
A0A5D2Q9Q2 6-135 None
A0A7J9HM95 5-148 None
A0A6A3BDL4 2-135 None
A0A4U5PPG8 77-199 None
A0A4S8IZJ2 111-273 None
A0A287E7P6 6-133 None
A0A061GP45 55-191 None
A0A834W227 55-189 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.