DPCstruct | MC14216

Metacluster Properties and Pfam Annotations

Number of structural domains42
Mean domain length (aa)75 ± 12 aa
Standard deviation of domain lengths11.57
Length coefficient of variation0.15
Mean AlphaFold2 pLDDT confidence score91.81
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.90
Mean intra-cluster local Distance Difference Test score0.88
Mean intra-cluster sequence similarity (%)52.34
Pfam Score100.00
Assigned Pfam label(s) CL0063

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A0U0SUA5 137-227 MVRDFQRIIGMEARVQIQGQAGRLPDAVVACVGGGSNAIGIFHAFLDDPGVRLVGFEAAGDGVETGRHAATFTAGSPGAFHGSFSYL…
K8PI23 3-79 SPGEEEQCVIGKETRLQMIEAEGRLPDSLVACIGDGSNAIGLFHPFLDEPTVEMYGVEAAGRGLKSGMHAASIVRGR
A0A6L5DCR6 295-385 None
A0A812SKT9 52-142 None
A0A447U2B0 131-212 None
A0A378C9T9 49-139 None
F4PSW7 205-272 None
A0A1S8VFD5 496-547 None
A0A1Q9CIZ3 53-104 None
A0A829WMI3 2-61 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.