DPCstruct | MC14172

Metacluster Properties and Pfam Annotations

Number of structural domains65
Mean domain length (aa)98 ± 15 aa
Standard deviation of domain lengths14.60
Length coefficient of variation0.15
Mean AlphaFold2 pLDDT confidence score80.81
Mean fraction of residues predicted as intrinsically disordered0.55
Mean length-normalized TM-Score0.65
Mean intra-cluster local Distance Difference Test score0.66
Mean intra-cluster sequence similarity (%)20.34
Pfam Score16.67
Assigned Pfam label(s) CL0123- PF18790- PF18821

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2T1B5A0 65-159 REVPPEIKAAAQQRFGADIRMGVPRENGLYKGEVFNTDRYLVQEVATRSVVFHDKQNMEFADSRLKWCNENQRLNGADVQVGYTGDQ…
C9YBG7 9-96 LDDMVAWVTASQGELEEVLAERQYCGPVLKMSEHHALQKIGRRNYTIHKLDELNSIPELNHPKTTIRYRDGRGSILDDDSLHGGGVAH
C6XEQ4 299-398 None
C6XEQ8 70-166 None
C6XEQ6 248-355 None
C6XEQ5 111-211 None
A0A5E7QH44 82-202 None
A0A848P2V5 236-335 None
A0A6S7ARC5 55-163 None
G9G7L8 22-151 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.