DPCstruct | MC14142

Metacluster Properties and Pfam Annotations

Number of structural domains130
Mean domain length (aa)109 ± 18 aa
Standard deviation of domain lengths18.31
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score84.05
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.72
Mean intra-cluster local Distance Difference Test score0.67
Mean intra-cluster sequence similarity (%)27.76
Pfam Score94.85
Assigned Pfam label(s) PF00347- CL0267- CL0376- CL0177- CL0269

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A397TZV5 140-249 GTTRALIANYIRGVSEGYKVSLKFVGVGYRASLESDGKLYLEVGYVNPVVMEIPPDIKCIVPAPTKIILSGTDKQLVYRFAAQIREH…
A0A096Y6X9 22-140 NIKKKYQIIKIIQQIKSLSTIKLKLTGVGFKVRNFLLNNCNKHFLQLFLGKSHKIFIVIPKDITLQSKKNVIKLSCYNLQTLNLFVV…
A0A7S2QP29 113-225 None
A0A7J6L6J7 549-673 None
A0A6V8HNK8 462-600 None
A0A803QES2 303-401 None
A0A645JIJ7 5-85 None
A0A834T6P5 328-456 None
A0A0K9QCB7 5-99 None
A0A821IKZ1 4-93 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.