DPCstruct | MC14130

Metacluster Properties and Pfam Annotations

Number of structural domains42
Mean domain length (aa)247 ± 35 aa
Standard deviation of domain lengths34.65
Length coefficient of variation0.14
Mean AlphaFold2 pLDDT confidence score77.11
Mean fraction of residues predicted as intrinsically disordered0.28
Mean length-normalized TM-Score0.47
Mean intra-cluster local Distance Difference Test score0.60
Mean intra-cluster sequence similarity (%)21.22
Pfam Score74.64
Assigned Pfam label(s) PF01424- CL0196- CL0221- CL0449

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2C9L1D4 233-446 DLVLIEHEEWSLDRQKHSHCILNQSATQCGCLLEWITEPENGCFRCTIKLQGEEISSCLAKQRKVAVSLASSKALFQLFESQPLVHR…
A0A182GMR0 207-492 FILLDDNLEDSGREFGMLNCGLFVVRVVSQERKQWVASVTAAGYLLSKSNGPKKKANRACREEALQLLRRKCYKIRTNPNRCWDSCN…
A0A182U7F9 684-939 None
A0A4Y2BE54 569-788 None
A0A094ZEF5 201-473 None
A0A6P9ABB2 318-569 None
A0A835NM68 334-572 None
L8Y3H6 253-500 None
A0A7J6BA45 953-1202 None
A0A5N6ED90 69-366 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.