DPCstruct | MC14128

Metacluster Properties and Pfam Annotations

Number of structural domains265
Mean domain length (aa)111 ± 20 aa
Standard deviation of domain lengths19.88
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score78.96
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.73
Mean intra-cluster local Distance Difference Test score0.76
Mean intra-cluster sequence similarity (%)38.63
Pfam Score97.56
Assigned Pfam label(s) PF04621- CL0123- CL0168- PF01130- PF20772

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A7RYB7 1-90 IQLWQFLLELLTDKTCRHLIMWVGEEGEFKLNDPEQVAQQWGKRKNKPAMNYEKLSRALRYYYDGDMIHKVHGKRFVYKFVCNLKNL…
A0A182GI37 16-117 GAPNTSSTGTGKPRQGGSHIHLWQFLKELLATPDQHGTAIRWIDRTKGVFKIEDSVRVARLWGRRKNRPAMNYDKLSRSIRQYYKKG…
A0A182FWX7 205-324 None
A0A182FHX1 31-110 None
A0A1D2NAZ0 187-314 None
A0A2B4SMQ1 491-615 None
A0A2B4SHU3 274-385 None
A0A2B4SFI0 664-772 None
A0A7E4WE70 2-99 None
A0A7E4VYD6 218-338 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.