DPCstruct | MC14120

Metacluster Properties and Pfam Annotations

Number of structural domains48
Mean domain length (aa)428 ± 76 aa
Standard deviation of domain lengths75.69
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score89.76
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.68
Mean intra-cluster local Distance Difference Test score0.71
Mean intra-cluster sequence similarity (%)33.15
Pfam Score97.10
Assigned Pfam label(s) PF12621- PF06415- CL0021- CL0088

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A538FCX4 210-659 SGTPVFDALWARYPHTTLDASGRAVGLPEGQMGNSEVGHLTIGSGRILDQDLQRVNRAIEEGSFFENAALVGAFERAKHRGTNVHLL…
A0A3P8KC69 2-386 GLLSPGGVHSLEDHLFKLIDMAHTYGLKKVSVHAFGDGRDVAPKSILDSLKKLQAQVDKYGYKIASIGGRFYGMDRDKMFDRVEKHY…
A0A084U447 26-514 None
A0A4Y7LDF0 36-452 None
A0A2G9ZM99 36-513 None
A0A381GWU9 2-235 None
A0A3L6RX52 405-851 None
A0A2P4VEA2 28-438 None
A0A7V6PWK2 2-314 None
A0A836AUN9 450-969 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.