DPCstruct | MC141

Metacluster Properties and Pfam Annotations

Number of structural domains12
Mean domain length (aa)196 ± 21 aa
Standard deviation of domain lengths21.36
Length coefficient of variation0.11
Mean AlphaFold2 pLDDT confidence score72.08
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.37
Mean intra-cluster local Distance Difference Test score0.65
Mean intra-cluster sequence similarity (%)25.04
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2H1E5N0 18-191 QGQEFSRNKVVKKITVLRDTILLAPTSIYPYDFKVFSLDNKLIDPKEYHVDFVKGKLILNKKRYGKIKVEYLEYPDFVTRRYTSFDK…
A0A4Q3U835 8-203 LKAQLNANQRLRKITTTSEIISLDSLSIVPQSIKVSYNENVQADTSLYQIDYAKATFLWKGAAGIELSLSYKVFPILFSKRYFHKDV…
A0A257LUE6 1-205 None
A0A2M7NMI1 2-248 None
A0A388Q339 10-202 None
A0A3C0ZQ23 23-232 None
A0A4Q6BE50 22-194 None
A0A351PXJ0 1-166 None
A0A090WAM1 1-186 None
A0A6M8V865 6-223 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.