DPCstruct | MC14090

Metacluster Properties and Pfam Annotations

Number of structural domains30
Mean domain length (aa)643 ± 91 aa
Standard deviation of domain lengths91.42
Length coefficient of variation0.14
Mean AlphaFold2 pLDDT confidence score70.22
Mean fraction of residues predicted as intrinsically disordered0.35
Mean length-normalized TM-Score0.54
Mean intra-cluster local Distance Difference Test score0.65
Mean intra-cluster sequence similarity (%)20.88
Pfam Score90.76
Assigned Pfam label(s) PF02671- PF08295- PF16879

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2I0T3M5 12-487 SWSEDSTFVSSKKTQYEEHIYRCEDERFELDVVLETNLATIRVLEAIQKKLSRLSAEEQAKFRLDNTLGGTSEVIHRKALQRIYADK…
A0A196SPA5 53-711 QTIGSEDFSYSHMRRNQYEEALFRCEDDHFEADVILETTRSAIAQLELLQKELEALEEDGAYKLREDALSAVQTAAIRRVYAHNGMD…
A0A7S2WDF1 2-646 None
A0A5K4F1Y2 25-791 None
A0A842ZFF9 2-498 None
A0A6I9Q1V0 68-674 None
Q6FNH7 275-866 None
A0A0K0EKT0 1035-1658 None
A0A6J3CBY4 16-690 None
A0A6S8VHN3 97-726 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.