DPCstruct | MC14061

Metacluster Properties and Pfam Annotations

Number of structural domains8
Mean domain length (aa)104 ± 9 aa
Standard deviation of domain lengths8.51
Length coefficient of variation0.08
Mean AlphaFold2 pLDDT confidence score90.97
Mean fraction of residues predicted as intrinsically disordered0.16
Mean length-normalized TM-Score0.84
Mean intra-cluster local Distance Difference Test score0.78
Mean intra-cluster sequence similarity (%)32.78
Pfam Score100.00
Assigned Pfam label(s) CL0236

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
E9S8F7 1-98 MFEWNTWRAMTILDGGNIVENIKSDDNGNPFSTASGNMADIVCDYGKFALAVEVTMQSGQKQYEMEGEPVSRHLAKLKNETGKEAYC…
R9LKP6 25-126 ETPAYLEWTLWRAALAIDHMVNKPYEVRGFKLDSDFMPVSAAGGGKGDLYCEFNDFTILTEVTMSTSSRQEAMEGEPVRRHVSDAVL…
A0A376CMN8 182-291 None
A0A5A4TU54 206-306 None
E6NMA4 2-96 None
A0A649Z413 293-401 None
A0A1W9QM73 1-121 None
A0A6L7ZKF5 2-95 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.