DPCstruct | MC14037

Metacluster Properties and Pfam Annotations

Number of structural domains14
Mean domain length (aa)226 ± 25 aa
Standard deviation of domain lengths25.45
Length coefficient of variation0.11
Mean AlphaFold2 pLDDT confidence score65.74
Mean fraction of residues predicted as intrinsically disordered0.86
Mean length-normalized TM-Score0.30
Mean intra-cluster local Distance Difference Test score0.81
Mean intra-cluster sequence similarity (%)41.39
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
V4M364 1-223 MDLETENRIASILLREAAELRRQAEKDGVRAYLEKPNVRHRPNSRFLTATVLGVQQSNKAVETNEMWRARQKEIELEDERLKRETRE…
A0A2V0P3S3 19-260 TGPEAQRRIAALLIAQAQQLEERAATDGATAFCGRPVQRERLNERFLANTLRGVASTNRRAQERQMWAAWEKEAPAAAAGAARQGAG…
A0A6J5VSX5 56-332 None
G7IFC3 1-224 None
A0A2K2C5C3 1-214 None
A0A835R629 1-208 None
Q7XIH0 11-248 None
A0A061RCR5 19-212 None
C1E1K4 10-187 None
A0A444Y4K6 108-345 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.