DPCstruct | MC14022

Metacluster Properties and Pfam Annotations

Number of structural domains116
Mean domain length (aa)113 ± 18 aa
Standard deviation of domain lengths18.07
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score84.46
Mean fraction of residues predicted as intrinsically disordered0.26
Mean length-normalized TM-Score0.69
Mean intra-cluster local Distance Difference Test score0.65
Mean intra-cluster sequence similarity (%)25.17
Pfam Score84.64
Assigned Pfam label(s) PF02625- CL0382- CL0063

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7K0JWU2 4-117 DLSGRSLELRAGRVPFVHARVTLAEAPTSAKPGDEAIIRADGAIEGFVGGVCAESTVREVATDLLASGAGPIVLRVTPEPEPDQPGR…
A0A536KL24 3-114 EVEIELARRLEAGEEVVLATVVRTDGAPPSAPGAKALLARESALAGTLGCSEFDSAAQADAAGLLDAGEPALRTYRHDLGSIEVYLE…
A0A535EJD9 3-111 None
A0A0P7YCI7 6-113 None
A0A4D4N402 3-117 None
A0A6L4Z5E0 2-138 None
A0A1Y2NLU0 3-118 None
A0A7C1A0B5 4-106 None
A0A244C3B4 21-130 None
A0A2N1S1I2 4-119 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.