DPCstruct | MC14017

Metacluster Properties and Pfam Annotations

Number of structural domains14
Mean domain length (aa)109 ± 13 aa
Standard deviation of domain lengths13.11
Length coefficient of variation0.12
Mean AlphaFold2 pLDDT confidence score79.44
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.80
Mean intra-cluster local Distance Difference Test score0.79
Mean intra-cluster sequence similarity (%)29.97
Pfam Score90.00
Assigned Pfam label(s) PF08707- PF19808

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
R5BC67 25-131 SPVVNTGDSADDVEIVIQRLEAGHIDITSGYDNWRDIGFAFADEFRENGRDYFHRVSRFHPDYDERNTDEQYDKCLRAHRTGVTLNT…
A0A1I6REB0 4-108 YRQLLTINIMRNLIRLSKPTEAFFRKSIKDIDKNSRDITKNYKYKNQLGLAFANTYGEQARDFFHIICKPNANYDKLKCNVEYTEYL…
K9ES57 3-96 None
A0A412X1P6 290-388 None
A0A7J0AW85 2-105 None
A0A2D8CJR4 131-234 None
A0A379MTH6 211-341 None
A0A379MNL4 220-323 None
A0A2V3PSR4 112-219 None
A0A1H4DDK9 5-92 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.