DPCstruct | MC14013

Metacluster Properties and Pfam Annotations

Number of structural domains14
Mean domain length (aa)283 ± 47 aa
Standard deviation of domain lengths47.10
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score70.84
Mean fraction of residues predicted as intrinsically disordered0.26
Mean length-normalized TM-Score0.62
Mean intra-cluster local Distance Difference Test score0.65
Mean intra-cluster sequence similarity (%)22.41
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2R8Q8J7 1-323 MPGMVLFRRRWSVGSDDLVLPAFFLFVLHCIWLVVLSVVLFGLPYSSEQSCSVTLVDHGRGYLGILVSCLICESAIMWLSMRGSILY…
A0A6S7JR12 7-317 FNRRWVVGSDDFVIPFGIAFVLRVIWMISLGVVLALYHSFDYDPYTASNFPYYECQSTFDYFTSGYIVLLFATNLLEFLVSWLSSKG…
A0A6H5IBC1 176-431 None
C1FDN2 1-392 None
A0A836B832 1-272 None
A0A0V1DF00 1-289 None
K1PNC0 44-399 None
A0A0R3T575 1-254 None
A0A564Y478 1-252 None
A0A1B6CRZ8 7-287 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.