DPCstruct | MC14012

Metacluster Properties and Pfam Annotations

Number of structural domains28
Mean domain length (aa)118 ± 17 aa
Standard deviation of domain lengths16.75
Length coefficient of variation0.14
Mean AlphaFold2 pLDDT confidence score90.95
Mean fraction of residues predicted as intrinsically disordered0.35
Mean length-normalized TM-Score0.78
Mean intra-cluster local Distance Difference Test score0.74
Mean intra-cluster sequence similarity (%)28.23
Pfam Score100.00
Assigned Pfam label(s) CL0044

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7Z0PTP9 259-380 DEIAHYYRFQQLEKGRYYQKGDEPGSPSGPELHVDWSAVYPVKPDLKLEHLAEDPHILAAAKEFNEFYAAFLAKINLAYKGQPNLLL…
A0A6S7JGK7 55-164 GKNADTFAYIGKSLPFDEDGVWPIVDNPMMSMYKDGTRAQHVAKSFSKTYWKLLEKLQNVFDGNTLLFGDTVAIMKDLLIHGNRLVQ…
A0A345T4E4 82-189 None
A0A3D9W6L6 1-146 None
A0A512BGS5 12-112 None
A0A1N7KT25 342-484 None
Q7USV4 245-365 None
A0A846CVX3 39-192 None
A0A7U4P7D2 135-262 None
A0A090KQ49 237-339 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.