DPCstruct | MC13999

Metacluster Properties and Pfam Annotations

Number of structural domains616
Mean domain length (aa)173 ± 38 aa
Standard deviation of domain lengths38.26
Length coefficient of variation0.22
Mean AlphaFold2 pLDDT confidence score89.63
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.46
Mean intra-cluster local Distance Difference Test score0.42
Mean intra-cluster sequence similarity (%)15.00
Pfam Score99.11
Assigned Pfam label(s) PF12631- CL0489- CL0063- CL0118- CL0015

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
E4Y9V0 108-322 None
D2VMT8 241-463 None
A0A5N9VZ30 3-123 None
A0A6M2CKK8 5-141 None
A0A8B6EXG2 987-1238 None
A0A368BPF0 10-178 None
A0A7V6Y9J5 137-363 None
A0A1E4SWR3 229-377 None
A0A840QD79 4-195 None
B7G2E2 359-538 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.