DPCstruct | MC13999

Metacluster Properties and Pfam Annotations

Number of structural domains616
Mean domain length (aa)173 ± 38 aa
Standard deviation of domain lengths38.26
Length coefficient of variation0.22
Mean AlphaFold2 pLDDT confidence score89.63
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.46
Mean intra-cluster local Distance Difference Test score0.42
Mean intra-cluster sequence similarity (%)15.00
Pfam Score99.11
Assigned Pfam label(s) PF12631- CL0489- CL0063- CL0118- CL0015

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7V3F7A4 28-218 None
A0A2P8Z0S6 143-272 None
A0A6A9T1B3 20-161 None
A0A6A5D6G6 111-242 None
A0A3E0VU17 2-156 None
A0A441CUG6 12-148 None
A0A2N5C5M5 2-166 None
A0A4T0JG42 522-745 None
A0A1A6AUB9 22-148 None
A0A1R0H9I3 89-221 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.