DPCstruct | MC13999

Metacluster Properties and Pfam Annotations

Number of structural domains616
Mean domain length (aa)173 ± 38 aa
Standard deviation of domain lengths38.26
Length coefficient of variation0.22
Mean AlphaFold2 pLDDT confidence score89.63
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.46
Mean intra-cluster local Distance Difference Test score0.42
Mean intra-cluster sequence similarity (%)15.00
Pfam Score99.11
Assigned Pfam label(s) PF12631- CL0489- CL0063- CL0118- CL0015

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A843CL22 112-242 VQAVSEIARTGAALIKDGDRILTHCNSKAALAPIIEAHRQGKKIEVYATESRPWRQGLLTIRDLAGAGVPVTLIIDSAVRRFMPDID…
A0A0W8FL13 5-167 SLKDKNNIAKKAASIVAEGSSVILGAGIPTKCLKFLNDKDCWVIYETGIIGACPFTCGTETIIDASRKKIGLREGGSIFDSSFIFSL…
R9PMB7 7-243 None
A0A350IWK3 22-152 None
K8ELV9 97-227 None
A0A370IFV3 336-560 None
A0A7S3ZPL2 395-524 None
A0A7V2XSJ5 123-284 None
N4X2A1 704-908 None
F4Q747 866-1075 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.