DPCstruct | MC13975

Metacluster Properties and Pfam Annotations

Number of structural domains58
Mean domain length (aa)213 ± 40 aa
Standard deviation of domain lengths39.87
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score86.67
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.68
Mean intra-cluster local Distance Difference Test score0.72
Mean intra-cluster sequence similarity (%)44.82
Pfam Score93.29
Assigned Pfam label(s) CL0328- PF00124- PF00421- PF05695

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2E0TH83 69-310 IGLNMLASVDWDVVQFIRQLPWLALEPPPPSAGLSIPTLQEGGWWLMAGFFLTASVILWWIRTYRRARALKMGTHVAWAFASAIWLY…
A0A2L1K3P2 29-251 PLYVGFFGVTTVFFSALGTGLILWGAALGPTWNIWQISIAPPDLSYGLGLAPLREGGLWQLITICALGAFVSWALRQVEISRKLGMG…
A0A4S8I8D8 42-305 None
A0A835IZ33 8-233 None
B9RRG9 2-188 None
A0A0E0JUB3 1-174 None
A0A2G3BHD9 2-152 None
A0A2I8BIJ1 2-263 None
A0A2G2XBZ1 1-263 None
A0A8A5RCG2 1-164 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.