DPCstruct | MC13965

Metacluster Properties and Pfam Annotations

Number of structural domains100
Mean domain length (aa)295 ± 58 aa
Standard deviation of domain lengths58.39
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score73.74
Mean fraction of residues predicted as intrinsically disordered0.36
Mean length-normalized TM-Score0.58
Mean intra-cluster local Distance Difference Test score0.70
Mean intra-cluster sequence similarity (%)32.94
Pfam Score89.05
Assigned Pfam label(s) CL0023- PF02272- PF01018- CL0127- PF09269

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A814TJS0 19-164 LNLPFIDKLRVYVRGGRGGNGLKKYGGIGGQGGHVLVHGKRNLTLKNVYEKNLAKRYIASDGEHSYKTCLNAQSGENLIIHVPLGIQ…
A0A0G1VJH6 1-301 MVPREGLEPSRDCSHAILSRARMPVPPPGQAKKRVYYIRFMFCDEVTVQFNAGRGGNGCVGFRREKFVPYGGPNGGDAGKGGSLYLM…
A0A0F8ALW7 590-950 None
A0A0K0EK14 1885-2200 None
A0A7Y4ZGZ5 1-309 None
A0A2H6K9W1 124-340 None
A0A5J4YLG7 160-504 None
A0A6J5W0C7 2-217 None
A0A5F5XVZ4 224-536 None
A0A3S3Q0V8 116-457 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.