DPCstruct | MC13949

Metacluster Properties and Pfam Annotations

Number of structural domains13
Mean domain length (aa)157 ± 14 aa
Standard deviation of domain lengths14.13
Length coefficient of variation0.09
Mean AlphaFold2 pLDDT confidence score84.01
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.67
Mean intra-cluster local Distance Difference Test score0.65
Mean intra-cluster sequence similarity (%)24.48
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A5C6X6K9 277-428 WAFQQWNTLSTYLKINADDPYGAVTGVFEHLTQGQGVYRDTYNEGVLREDLTEIPPLWDRLKFGAWYRGAGDVRRVMDDIYVAVGPG…
A0A2E5MRH9 3-165 EGSQPDYSGWKGNTGEWNRLELLANSDEGTIKTWTNGELIHSVTNYKKEDTPEGLSIALIGFDPNYADRYSSLVFRMDDIYVSSSPA…
A0A2D5EKL7 63-221 None
A0A3C1ERE3 2-160 None
A0A0F2QQM5 182-358 None
D2W455 27-186 None
A0A0B5BG24 49-207 None
A0A5C6UVH4 121-274 None
A0A328C1F3 2-140 None
A0A849YZ09 89-238 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.