DPCstruct | MC13935

Metacluster Properties and Pfam Annotations

Number of structural domains69
Mean domain length (aa)163 ± 31 aa
Standard deviation of domain lengths30.93
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score69.42
Mean fraction of residues predicted as intrinsically disordered0.36
Mean length-normalized TM-Score0.56
Mean intra-cluster local Distance Difference Test score0.71
Mean intra-cluster sequence similarity (%)31.32
Pfam Score100.00
Assigned Pfam label(s) CL0023

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1B8XS38 2-121 EEFELRKAAARAVTGVLASHPNSTDVHIINMSLTFHGQELLSDTTIELNSGRRYGLIGLNGTGKSMLLSAVGGREVPIPEHIDIYHL…
A0A2G2XTF2 18-158 AAKRGGKGAATSKAAAAKVAVAESNEVDNLANGVEDLKISDRTCTGVLCSHPFLRDIRIESLSVTFHGYDLIVYSELDLNYGRCCGL…
E4YFR2 2-98 None
A0A565AP77 96-212 None
A0A183KQI8 126-294 None
A0A183KCP5 12-206 None
A0A4Y9ZX65 73-268 None
A0A6V7NQY4 10-167 None
A0A7S3ZUU2 583-738 None
K2GZ72 141-298 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.