DPCstruct | MC13913

Metacluster Properties and Pfam Annotations

Number of structural domains12
Mean domain length (aa)103 ± 28 aa
Standard deviation of domain lengths27.54
Length coefficient of variation0.27
Mean AlphaFold2 pLDDT confidence score88.69
Mean fraction of residues predicted as intrinsically disordered0.29
Mean length-normalized TM-Score0.88
Mean intra-cluster local Distance Difference Test score0.88
Mean intra-cluster sequence similarity (%)53.48
Pfam Score100.00
Assigned Pfam label(s) CL0105

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A137QBF5 150-222 MFNSALEIAKFEGANIKTVSGIRGQVKKALPKPDDAFRATFEDKVLKSDLTFLRAWYSIEPRKFYKPVTLLLP
D7TUQ9 1-90 MFTSDLEIARFESAGVQTASGIKGQVKETAKEELGNQPKKKRGLPREGIARCTFEDRILVSNLVLLRAWIEVEVPCFFNPLTTALQP…
A0A438GV60 76-226 None
A0A6N2LU03 674-819 None
A0A0D2LTC9 762-842 None
A0A6N2LEQ5 131-259 None
A0A7G2CHD3 1-87 None
A0A6P5EUN7 812-900 None
A0A7R9JWZ4 269-344 None
A0A4P9YY49 241-330 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.